Table 2. Multiple regression analysis of the HOMA-Adiponectin and HOMA-IR with clamp-derived insulin sensitivity index.
Dependent variable | Model | Independent variables | B | 95% CI | P-value | R2 for model |
---|---|---|---|---|---|---|
ISI, mg/kgLBM-1. min-1 per mU/L x 100a,b | 1 | HOMA-Adiponectina | -0.441 | -0.581 to -0.300 | < 0.001 | 0.471 |
Sexc | 0.083 | -0.065 to 0.231 | 0.264 | |||
Tanner staged | -0.122 | -0.276 to 0.032 | 0.117 | |||
2 | HOMA-Adiponectina | -0.349 | -0.506 to -0.192 | < 0.001 | 0.521 | |
Sexd | 0.123 | -0.23 to 0.269 | 0.097 | |||
Tanner staged | -0.125 | -0.273 to 0.023 | 0.096 | |||
Waist circumference-to-height ratio | -1.018 | -1.907 to -0.128 | 0.026 | |||
3 | HOMA-IRa | -1.049 | -1.282 to -0.817 | < 0.001 | 0.638 | |
Sexd | -0.011 | -0.135 to 0.113 | 0.856 | |||
Tanner staged | 0.008 | -0.125 to 0.142 | 0.899 | |||
4 | HOMA-IRa | -0.968 | -1.259 to -0.676 | < 0.001 | 0.644 | |
Sexd | 0.011 | -0.122 to 0.145 | 0.867 | |||
Tanner staged | -0.003 | -0.138 to 0.133 | 0.968 | |||
Waist circumference-to-height ratio | -0.384 | -1.207 to 0.439 | 0.353 |
Abbreviations: B, unstandardized coefficient; CI, confidence interval; ISI, insulin sensitivity index; LBM, lean body mass; HOMA-Adiponectin, homeostasis model assessment of adiponectin; HOMA-IR, homeostasis model assessment of insulin resistance; NA, not applicable
aLogarithmic transformation was performed.
bInsulin sensitivity index (ISI) expressed as milligrams of glucose infused per kilogram of lean body mass (LBM) per minute.
c0 represents the female and 1 the male.
d0 represents the postpubertal stage and 1 the pubertal stage