Table 2.
Arboviral Studies and Cerebrospinal Fluid
| Variable (reference)a | PSOD 3 (Presentation OSH) | PSOD 13 | PSOD 63 | ||
|---|---|---|---|---|---|
| Arboviral Studies | |||||
|
|
|
||||
| Zika | PCR | Serum | ZIKV RT-PCR (+) | ZIKV RT-PCR (−) | |
|
|
|||||
| Urine | ZIKV RT-PCR (+) | ZIKV RT-PCR (+) | |||
|
|
|||||
| Cerebrospinal Fluid | ZIKV RT-PCR (−) | ||||
|
| |||||
| IgM ELISA | Serumb | Negative | Presumptive Positive | Presumptive Positive | |
|
| |||||
| Cerebrospinal Fluid | Presumptive Positive | ||||
|
| |||||
| Serum | PRNTc | Zika | Negative (<10) | Positive (320) | Positive (320) |
|
| |||||
| Dengue | Positive (160) | Positive (20,480) | Positive (2,560) | ||
|
| |||||
| Dengue | (<1.65) | IgM 1.58 ISR | |||
|
|
|||||
| (<1.65) | IgG 7.72 ISR | ||||
|
|
|||||
| West Nile | (−) | ||||
|
|
|||||
| Chikungunya | IgM (−) | ||||
|
|
|||||
| IgG (−) | |||||
| Cerebrospinal Fluidd | |||||
|
|
|
||||
| Glucose | (40–80) | 71 | |||
|
|
|
||||
| Protein | (15–45) | 51.5 | |||
|
|
|
||||
| Red Blood Cell | (0–3) | 4 | |||
|
|
|
||||
| White Blood Cell | (0–5) | 6 | |||
|
|
|
||||
| Differentials (%) | Neutrophils | (0–7) | 12 | ||
|
|
|
||||
| Lymphocytes | (28–96) | 78 | |||
|
|
|
||||
| Monocytes | (16–56) | 10 | |||
a
Human Immunodeficiency Virus, Herpes Simplex Virus Type 1 and 2, Hepatitis C, Syphilis antibody, Lyme, oligoclonal bands, John Cunningham virus in Cerebrospinal Fluid negative. Epstein-Barre Virus and Cytomegalovirus were IgG positive, IgM negative.
b
Zika IgM Antibody Capture Enzyme-Linked Immunosorbent Assay (Zika MAC-ELISA)
c
Arbovirus Plaque Reduction Neutralization Test (PRNT)
d
Cerebrospinal Fluid- only 50 white blood cells seen on cytospin smear Gram stain, Varicella-Zoster and Lyme Total Antibody screen- negative.