Table 1. Model parameter values.

The channel kinetics, intracellular Ca²⁺ dynamics and the corresponding parameter values, were derived from previous models (see Jasinski et al., 2013) and the references therein).

Channel	Parameters
$I_{Na}$	${\stackrel{-}{g}}_{Na}=150.0nS$, $E_{Na}=55.0mV$,${\displaystyle V_{m_{1/2}}=-43.8mV}$, $k_m=6.0mV$,$V_{\tau m_{1/2}}=-43.8mV$, $k_{{\tau }_m}=14.0mV$, ${\tau }_{m_{max}}=0.25ms$,${\displaystyle V_{h_{1/2}}=-67.5mV}$, $k_h=-10.8mV$,$V_{\tau h_{1/2}}=-67.5mV$, $k_{{\tau }_h}=12.8mV$, ${\tau }_{h_{max}}=8.46ms$
$I_K$	${\stackrel{-}{g}}_K=160.0nS$, $E_K=-94.0mV$, ${\displaystyle A_{\alpha }=0.01}$, $B_{\alpha }=44.0mV$, ${\kappa }_{\alpha }=5.0mV$ ${\displaystyle A_{\beta }=0.17}$, $B_{\beta }=49.0mV$, ${\kappa }_{\beta }=40.0mV$
$I_{Leak}$	${\stackrel{-}{g}}_{Leak}=2.5nS$, $E_{Leak}=-68.0mV$
$I_{NaP}$	${\displaystyle {\stackrel{-}{g}}_{NaP}\in [0.0,5.0]nS}$, ${\displaystyle V_{m_{1/2}}=-47.1mV}$, $k_m=3.1mV$, $V_{\tau m_{1/2}}=-47.1mV$, $k_{{\tau }_m}=6.2mV$, ${\tau }_{m_{max}}=1.0ms$, ${\displaystyle V_{h_{1/2}}=-60.0mV}$, $k_h=-9.0mV$, $V_{\tau h_{1/2}}=-60.0mV$, $k_{{\tau }_h}=9.0mV$, ${\tau }_{h_{max}}=5000ms$
$I_{CAN}$	${\displaystyle {\stackrel{-}{g}}_{CAN}\in [0.5,1.5]nS}$, $E_{CAN}=0.0mV,$ ${Ca}_{1/2}=0.00074mM$, ${\displaystyle n=0.97}$
$I_{Ca}$	${\stackrel{-}{g}}_{Ca}=0.01nS$, $E_{Ca}=R\bullet T/F\bullet ln\left({\left[Ca\right]}_{out}/{\left[Ca\right]}_{in}\right)$, $R=8.314J/(mol\bullet K)$, $T=308.0K$, $F=96.485kC/mol$, ${\left[Ca\right]}_{out}=4.0mM$ ${\displaystyle V_{m_{1/2}}=-27.5mV}$, $k_m=5.7mV$, ${\tau }_m=0.5ms$, ${\displaystyle V_{h_{1/2}}=-52.4mV}$, $k_h=-5.2mV$, ${\tau }_h=18.0ms$
${Ca}_{in}$	${\alpha }_{Ca}=2.5\bullet {10}^{-5}mM/fC$, $P_{Ca}=0.01$, $C{a}_{min}=1.0\bullet {10}^{-10}mM$, ${\displaystyle {\tau }_{Ca}=50.0ms}$
$I_{Syn}$	$g_{Tonic}=0.31nS$, $E_{Syn}=-10.0mV$, ${\tau }_{Syn}=5.0ms$