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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Stroke. 2019 Apr;50(4):978–988. doi: 10.1161/STROKEAHA.118.021590

Figure 2. Mitoquinone (MitoQ) attenuated short-term neurological deficits, oxidative stress and neuronal death and increased the expression of Nrf2 and PHB2 after subarachnoid hemorrhage (SAH).

Figure 2.

(A) Modified Garcia and beam balance scores. n=6 per group. (B) Double immunofluorescence staining and quantifications for Nrf2 (red) and PHB2 (red) in neuron (NeuN, green) of Sham, SAH+vehicle and SAH+MitoQ groups. Nuclei are stained with DAPI (blue). Top panel indicates the location of staining (small red box). Arrows indicate a cell chosen for 10 times magnification in right upper corner of merged panels. n=3 per group. (C) DHE and FJC staining in three groups above. (D) The quantifications of DHE and FJC staining. n=3 per group. Scale bar = 50μm. Data of Modified Garcia and beam balance scores were expressed as the medians with interquartile range using Kruskal–Wallis test followed by the Dunn’s post hoc test. Other data were expressed as the means ± SD using one-way analysis of variance (ANOVA) followed by the Tukey post hoc test. #P < 0.05 vs. Sham group; ##P < 0.01 vs. Sham group; *P < 0.05 vs. SAH+vehicle group.