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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Stroke. 2019 Apr;50(4):978–988. doi: 10.1161/STROKEAHA.118.021590

Figure 5. Blokade of Nrf2 and PHB2 reversed the effects of mitoquinone (MitoQ) on the oxidative stress-induced neuronal death 24 h after subarachnoid hemorrhage (SAH).

Figure 5.

(A) Representative images and (B) quantitative analyses of Double staining for DHE and FJC. (C) MDA levels. (D) Representative Western blot images and quantitative analyses of Bcl-xl, Bax, Cleaved Caspase-3 and Romo1. Data of Cleaved Caspase-3 protein expression was expressed as the medians with interquartile range using Kruskal–Wallis test followed by the Dunn’s post hoc test. Other data were expressed as the means ± SD using one-way analysis of variance (ANOVA) followed by the Tukey post hoc test. #P <0.05 vs. Sham group; *P < 0.05 vs. SAH+vehicle group. &P< 0.05 vs. SAH+ML385+MitoQ group; @P< 0.05 vs. SAH+PHB2 siRNA+MitoQ group.