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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Hepatology. 2019 Mar 25;69(4):1803–1815. doi: 10.1002/hep.30289

Figure 4.

Figure 4.

Schematic depiction of an integrated systems biology-based approach to sub-classifying iCCAs into distinct subgroups having important clinical implications for their diagnosis, prognosis, and targeted treatment designs. Adapted from Wang XW and Thorgeirsson SS (29). iCCA, intrahepatic cholangiocarcinoma; SNP, Single nucleotide polymorphism.