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. 2019 Mar 25;2019(3):CD012387. doi: 10.1002/14651858.CD012387.pub2

Hilarius 2008.

Methods Sequential cohort design with repeated measures ‐ with intervention group (IG) and control group (CG)
Participants Cancer patients who were to begin adjuvant or palliative chemotherapy treatment
Country: the Netherlands
Age: Participants: IG: mean 57 years; CG: mean 55 years, P = 0.17; Nurses: mean 36 years (26 to 48)
Sex: Participants: IG: 61% female; CG: 67% female, P = 0.54; Nurses: 100% female
Inclusion criteria
  1. cancer patient

  2. to begin adjuvant or palliative chemotherapy treatment


Exclusion criteria: Patients
  1. aged < 18 years

  2. lack basic proficiency in Dutch

  3. exhibit overt psychopathology or serious cognitive problems

  4. participating in a concurrent HRQoL study


N recruited: Participants: N = 298; IG: n = 148; CG: n = 150; Nurses: N = 10
N in analysis: Participants: N = 219; IG: n = 111; CG: n = 108; Nurses: N = 10
Interventions Content of screen:HRQoL: tool = EORTC QLQ‐C30: validated HRQoL measure with 5 functional scales, 9 symptom scales, and 2 General Health and QoL items, no total score can be computed. If applicable, a specific module for breast cancer (QLQ‐BR23), colorectal cancer (QLQ‐CR38), or lung cancer (QLQ‐LC13) was added.
Screenings interventionist: No interventionist for screening act, self‐completion of screening tool.
Intervention procedure:Solitary SI: Participants completed the EORTC questionnaire on touch screen computer in outpatient clinic. A graphic results summary was generated and given to participant and nurse before consultation (outpatient visit 2, 3, 4, 5 = study visit 1, 2, 3, 4). No specific guidelines were provided on how the HRQoL summary data could/should be used during consultations
Conditions for implementation
  1. a system/person is needed to deliver and collect questionnaires and to control data management

  2. a group educational session and written information for nurses on how to interpret the HRQoL summary scores

  3. development of written materials for (intervention) participants


Comparative condition: CG: usual care
Length of follow‐up: 4 consecutive outpatient visits
Outcomes Primary outcomes
  1. nurse‐patient communication: self‐report questionnaire for participants

  2. nurses' awareness of participants' HRQoL: COOP and WONCA completed by nurses and participants

  3. patient management: notations relating to HRQoL‐related topics covered by the EORTC questionnaires abstracted form medical and nursing records, and abstracted with a checklist

  4. patient satisfaction: modified PSQ, Form II with 4 subscales (perceived technical quality of care interpersonal manner, communication, and continuity of care)

  5. participants' HRQoL: SF‐36, and if applicable FACT‐B, FACT‐C, and FACT‐L

  6. participant and nurse evaluation of the intervention


Secondary outcomes: /
Outcome time points: Second outpatient visit (first study visit = baseline); fifth outpatient visit (fourth study visit)
Notes For bias judgement on NRCTs, see Table 3; Table 4; Table 9