7.

Prognosis of metastatic renal cancer

Risk factors	MSKCC risk model		IMDC risk model
MSKCC, Memorial Sloan Kettering Cancer Center; IMDC, International Metastatic Renal CellCarcinoma Database Consortium; ULN, upper limit of normal.
1	Time from diagnosis to treatment	<12 months	Time from diagnosis to treatment	<12 months
2	Karnofsky performance status	<80%	Karnofsky performance status	<80%
3	Corrected serum calcium	>10.0 mg/dL (2.4 mmol/L)	Corrected serum calcium	>10.0 mg/dL (2.4 mmol/L)
4	Hemoglobin	<Lower limit of laboratory reference range	Hemoglobin	<Lower limit of laboratory reference range
5	Elevated lactate dehydrogenase	>1.5 times ULN	Absolute neutrophil count (neutrophilia)	>ULN
6			Platelets (thrombocytosis)	>ULN
Risk grouping
Low-risk	0 factor		0 factor
Intermediate-risk	1−2 factors		1−2 factors
High-risk	3−5 factors		3−6 factors