2.

Comparison of muscle-invasive bladder cancer and its subtypes between WHO 2004 classification system and WHO 2016 classification system

2004 version	2016 version
Invasive urothelial tumors	Invasive urothelial tumors
Infiltrating urothelial carcinoma	Infiltrating urothelial carcinoma with divergent differentiation
with squamous differentiation	Nested, including large nested
with glandular differentiation	Microcystic
with trophoblastic differentiation	Micropapillary
Nested	Lymphoepithelioma-like
Microcystic	Plasmacytoid/signet ring cell/diffuse
Micropapillary	Sarcomatoid
Lymphoepithelioma-like	Giant cell
Lymphoma-like	Poorly differentiated
Plasmacytoid	Lipid rich
Sarcomatoid	Clear cell
Giant cell	Tumors of maullerian type
Undifferentiated	Tumors arising in a bladder diverticulum