TABLE 2.
Baseline characteristics of subjects undergoing functional endoscopic sinus surgery for high-grade chronic rhinosinusitis after randomization to anesthetic treatment arms*
| Characteristics | Total intravenous anesthetic (n = 37) | Inhaled anesthetic (n = 35) | p |
|---|---|---|---|
| Demographics | |||
| Age (years), mean [IQR] | 45 [20–77] | 55 [25–81] | 0.234 |
| Gender, n (%) | 0.299 | ||
| Female | 16(43.2) | 11 (31.4) | |
| Male | 21 (56.8) | 24 (68.6) | |
| BMI (kg/m2), mean [IQR] | 31 [21–56] | 28 [19–53] | 0.099 |
| ASA PS, n (%) | 0.854 | ||
| I | 2 (5.4) | 3 (8.6) | |
| II | 28 (75.7) | 25(71.4) | |
| III | 7(18.9) | 7 (20.0) | |
| Disease factors | |||
| Polyposis | 31 (83.8) | 33 (94.3) | 0.156 |
| Tissue eosinophilia | 28 (75.7) | 30 (85.7) | 0.282 |
| AFRS | 5(13.5) | 3 (8.6) | 0.505 |
| AERD | 3(8.1) | 3 (8.6) | 0.943 |
| Patient assessments | |||
| Lund-Mackay score, median [IQR] | 14 [13–16] | 15 [13–20] | 0.714 |
| SNOT-22 score, median [IQR] | 48.0 [37–59] | 45.5 [27–58] | 0.327 |
| Comorbidities, n (%) | |||
| Systemic hypertension | 16(43.2) | 13(37.1) | 0.598 |
| Diabetes mellitus | 2 (5.4) | 3 (8.6) | 0.597 |
| Reactive airway disease | 16(43.2) | 16(45.7) | 0.833 |
| Coronary artery disease | 1 (2.7) | 1 (2.9) | 0.968 |
| Renal disease | 0(0) | 2 (5.7) | 0.086 |
| Non-sinus dysrhythmias | 0(0) | 1 (2.9) | 0.227 |
| Congestive heart failure | 1 (2.7) | 0(0) | 0.246 |
| Tobacco use | 8(21.6) | 13(37.1) | 0.146 |
| COPD | 3(8.1) | 4 (11.4) | 0.634 |
| Peripheral vascular disease | 3(8.1) | 1 (2.9) | 0.320 |
| Liver disease | 2 (5.4) | 0(0) | 0.099 |
*
Values of p < 0.05 are considered statistically significant.
AERD = aspirin-exacerbated respiratory disease; AFRS = allergic fungal rhinosinusitis; ASA PS = American Society of Anesthesiologists’ Physical Status Score; BMI body mass index; COPD = chronic obstructive pulmonary disease; IQR = 25%–75% interquartile range; SNOT-22 = 22-item Sino-Nasal Outcome Test.