Table 1. AUCs of Quantitative 3D-cHRCT Values in Relation to the Physiological Diagnosis of ILD Progression.
| TA Ratio† | HAA Ratio | %HAA Ratio | ||||
|---|---|---|---|---|---|---|
| AUC (95% CI) |
P-value | AUC (95% CI) |
P-value | AUC (95% CI) |
P-value | |
| 5 mm* | 0.733
(0.582 – 0.884) |
.003 | 0.679
(0.506 – 0.851) |
.042 | 0.700
(0.538 – 0.861) |
.015 |
| 10 mm | 0.769
(0.628 – 0.910) |
<.001 | 0.710
(0.554 – 0.867) |
.009 | 0.744
(0.593 – 0.894) |
.002 |
| 20 mm | 0.769
(0.630 – 0.908) |
<.001 | 0.700
(0.525 – 0.874) |
.025 | 0.815
(0.677 – 0.953) |
<.001 |
| 30 mm | 0.733
(0.588 – 0.878) |
.002 | 0.754
(0.604 – 0.905) |
<.001 | 0.777
(0.630 – 0.924) |
<.001 |
3D-cHRCT, three-dimensional curved high-resolution computed tomography; AUC, Area under the receiver operating characteristic curve; CI, confidence interval; HAA, high attenuation area; ILD, interstitial lung disease; TA, total area
*the distance of 3D-cHRCT images from the chest wall
†Ratio of the follow-up to baseline