Table 2.
List of miRNAs showing concentration changes in the study
| miRNA | Obese (BMI >30) vs normal (BMI <25) | Progressors vs non‐progressors | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Progressors vs non‐progressors | Progressors | non‐progressors | Normal (BMI <25) | Obese (BMI >30) | ||||||||||||
| PO vs PN | NPO vs NPN | PN vs NPN | PO vs NPO | |||||||||||||
| Log 2 FC (> 1.5 fold change) | Log 2 FC (> 1.2 fold change) | P‐value | B‐H FDR | Log 2 FC (> 1.5 fold change | P‐value | B‐H FDR | Log 2 FC (> 1.5 fold change | P‐value | B‐H FDR | Log 2 FC (> 1.5 fold change | P‐value | B‐H FDR | Log 2 FC (> 1.5 fold change | P‐value | B‐H FDR | |
| let‐7b‐5p | — | 0.23 | 0.0182 | 0.0428 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐100‐5p | — | 0.46 | 0.003 | 0.0136 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐106b‐3p | — | 0.43 | 0.0082 | 0.0224 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐10a‐5p | — | 0.32 | 0.0372 | 0.0507 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐10b‐3p | — | 0.35 | 0.0227 | 0.0442 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐10b‐5p | — | 0.45 | 0.0093 | 0.0244 | — | — | — | — | — | — | 0.75 | 0.041 | 0.0501 | — | — | — |
| miR‐122‐5p | 0.66 | 0.66 | 0.0004 | 0.0091 | 0.95 | 0.0125 | 0.0395 | — | — | — | — | — | — | 0.86 | 0.0239 | 0.0451 |
| miR‐1246‐5p | — | 0.32 | 0.0416 | 0.0516 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐1249‐3p | — | — | — | — | — | — | — | ‐0.62 | 0.0251 | 0.0552 | — | — | — | — | — | — |
| miR‐125b‐1‐5p | — | 0.3 | 0.0216 | 0.0446 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐127‐5p | — | 0.51 | 0.0082 | 0.0233 | 1.02 | 0.0092 | 0.0776 | — | — | — | — | — | — | 0.82 | 0.0302 | 0.0399 |
| miR‐1296‐5p | — | — | — | — | ‐0.75 | 0.0111 | 0.0468 | — | — | — | 0.72 | 0.0228 | 0.0418 | — | — | — |
| miR‐134‐5p | — | 0.4 | 0.0495 | 0.0553 | 1.02 | 0.0156 | 0.0395 | — | — | — | — | — | — | — | — | — |
| miR‐136‐5p | — | — | — | — | 1.2 | 0.001 | 0.0253 | — | — | — | — | — | — | 0.76 | 0.04 | 0.0352 |
| miR‐143‐3p | — | — | — | — | ‐0.66 | 0.0251 | 0.0397 | — | — | — | — | — | — | — | — | — |
| miR‐144‐3p | — | 0.39 | 0.0231 | 0.0438 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐144‐5p | — | — | — | — | — | — | — | — | — | — | 0.69 | 0.0212 | 0.0466 | — | — | — |
| miR‐145‐5p | — | 0.48 | 0.0065 | 0.0193 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐150‐5p | — | 0.45 | 0.005 | 0.0179 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐155‐5p | — | — | — | — | — | — | — | — | — | — | 0.84 | 0.0181 | 0.0498 | — | — | — |
| miR‐17‐3p | — | 0.44 | 0.0291 | 0.0496 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐181a‐1‐3p | — | 0.39 | 0.0222 | 0.0445 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐183‐5p | — | — | — | — | — | — | — | — | — | — | 0.93 | 0.0083 | 0.0457 | — | — | — |
| miR‐190a‐5p | — | 0.53 | 0.0005 | 0.0068 | — | — | — | — | — | — | — | — | — | 0.79 | 0.0062 | 0.0409 |
| miR‐192‐5p | — | 0.52 | 0.0008 | 0.0068 | — | — | — | — | — | — | — | — | — | 0.62 | 0.0404 | 0.0333 |
| miR‐193a‐3p | — | 0.39 | 0.0049 | 0.0186 | 0.66 | 0.0461 | 0.0507 | — | — | — | — | — | — | 0.61 | 0.0405 | 0.0314 |
| miR‐193a‐5p | — | 0.48 | 0.0028 | 0.0136 | — | — | — | — | — | — | — | — | — | 0.76 | 0.0231 | 0.0508 |
| miR‐193b‐3p | — | 0.52 | 0.002 | 0.0136 | 0.8 | 0.0095 | 0.0601 | — | — | — | — | — | — | — | — | — |
| miR‐210‐3p | 0.61 | 0.61 | 0.0026 | 0.0136 | — | — | — | — | — | — | — | — | — | 0.78 | 0.0274 | 0.0402 |
| miR‐214‐3p | — | — | — | — | ‐0.7 | 0.013 | 0.0365 | — | — | — | 0.88 | 0.0076 | 0.0836 | — | — | — |
| miR‐215‐5p | — | 0.33 | 0.0347 | 0.0526 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐23a‐5p | — | — | — | — | 0.85 | 0.0318 | 0.0447 | — | — | — | — | — | — | — | — | — |
| miR‐23b‐3p | — | 0.27 | 0.0455 | 0.0544 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐24‐2‐5p | — | 0.39 | 0.0395 | 0.0518 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐29a‐5p | — | 0.45 | 0.0012 | 0.0091 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐29c‐5p | — | 0.45 | 0.0105 | 0.0265 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐3200‐3p | 0.61 | 0.61 | 0.0004 | 0.0068 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐320a‐3p | — | 0.38 | 0.0254 | 0.0468 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐320b‐1‐3p | — | 0.33 | 0.0284 | 0.0497 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐326‐3p | — | — | — | — | 0.78 | 0.0409 | 0.0517 | — | — | — | — | — | — | — | — | — |
| miR‐33b‐5p | — | — | — | — | 1.02 | 0.0124 | 0.0448 | — | — | — | — | — | — | — | — | — |
| miR‐34a‐5p | — | 0.29 | 0.0385 | 0.0515 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐3615‐3p | — | 0.31 | 0.019 | 0.0418 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐365a‐3p | — | — | — | — | — | — | — | — | — | — | 0.8 | 0.0105 | 0.0385 | — | — | — |
| miR‐370‐3p | — | 0.35 | 0.0321 | 0.0509 | 0.78 | 0.0249 | 0.0420 | — | — | — | — | — | — | — | — | — |
| miR‐375‐3p | — | 0.31 | 0.0355 | 0.0515 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐376b‐3p | 0.66 | 0.66 | 0.012 | 0.0292 | 1.42 | 0.0067 | 0.0848 | — | — | — | — | — | — | — | — | — |
| miR‐377‐3p | — | — | — | — | 1.08 | 0.023 | 0.0485 | — | — | — | — | — | — | — | — | — |
| miR‐378a‐3p | 0.62 | 0.62 | 0.0008 | 0.0078 | 0.78 | 0.0368 | 0.0490 | — | — | — | — | — | — | 0.86 | 0.0192 | 0.0634 |
| miR‐4440‐3p | — | — | — | — | — | — | — | — | — | — | 0.91 | 0.0315 | 0.0495 | — | — | — |
| miR‐4508‐5p | — | — | — | — | 0.79 | 0.0457 | 0.0526 | — | — | — | — | — | — | — | — | — |
| miR‐451a‐3p | — | 0.32 | 0.041 | 0.0518 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐4532‐5p | 0.66 | 0.66 | 0.0033 | 0.0141 | 1.01 | 0.0226 | 0.0520 | — | — | — | — | — | — | 1.04 | 0.024 | 0.0396 |
| miR‐483‐5p | 0.59 | 0.59 | 0.002 | 0.0124 | 0.85 | 0.0249 | 0.0450 | — | — | — | — | — | — | 0.84 | 0.0324 | 0.0356 |
| miR‐487b‐3p | — | 0.4 | 0.0351 | 0.0520 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐490‐3p | — | — | — | — | — | — | — | — | — | — | — | — | — | 0.73 | 0.05 | 0.0367 |
| miR‐500a‐3p | — | 0.3 | 0.0271 | 0.0486 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐501‐5p | — | 0.51 | 0.0002 | 0.0068 | — | — | — | — | — | — | — | — | — | 0.63 | 0.0132 | 0.0381 |
| miR‐505‐3p | — | 0.46 | 0.0058 | 0.0198 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐548q‐5p | — | 0.32 | 0.0197 | 0.0420 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐550a‐1‐3p | — | 0.55 | 0.0005 | 0.0057 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐576‐3p | — | — | — | — | 0.72 | 0.0239 | 0.0465 | — | — | — | — | — | — | 0.6 | 0.0359 | 0.0365 |
| miR‐6087‐3p | — | 0.51 | 0.0033 | 0.0132 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐6087‐5p | — | 0.47 | 0.0059 | 0.0192 | 0.77 | 0.0317 | 0.0472 | — | — | — | — | — | — | 0.78 | 0.0212 | 0.0560 |
| miR‐627‐5p | — | 0.42 | 0.0335 | 0.0519 | 0.83 | 0.0426 | 0.0513 | — | — | — | — | — | — | — | — | — |
| miR‐660‐3p | 0.63 | 0.63 | 0.0001 | 0.0068 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐671‐5p | — | — | — | — | 0.67 | 0.0101 | 0.0511 | — | — | — | — | — | — | — | — | — |
| miR‐7‐1‐5p | — | 0.34 | 0.0059 | 0.0183 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐7641‐1‐3p | — | 0.37 | 0.019 | 0.0432 | — | — | — | — | — | — | — | — | — | 1.04 | 0.0005 | 0.0066 |
| miR‐874‐3p | — | 0.32 | 0.0441 | 0.0537 | — | — | — | — | — | — | — | — | — | — | — | — |
| miR‐99a‐5p | — | 0.50 | 0.0021 | 0.0119 | — | — | — | — | — | — | — | — | — | — | — | — |
B‐H FDR, Benjamini‐Hochberg False Discovery Rate; NPN, non‐progressors normal; NPO, non‐progressors obese; PN, progressors normal; PO, Progressors Obese.