Figure 3.

L‐type amino acid transporter 1 (LAT1) inhibition impairs MB cell migration. A, Scratch‐wound assay on a DAOY cell confluent layer treated or not with JPH203 at the indicated concentrations and on which a ‘mechanical’ wound was made at time 0. B, Dot plot showing quantitative determination of wound closure after 8 h in the absence or presence of the indicated concentrations of JPH203. The results are expressed as the percentage of closure of each individual wound relative to time 0. The bars represent the mean ± SEM for each experimental condition (**P < 0.01, Student's t test)