Table 2.
Normal | TAC | TAC + Veh | TAC + AA | F value | P value | |
---|---|---|---|---|---|---|
Parameters | ||||||
Body weight (g) | 38.57 ± 2.99 | 39.13 ± 4.32 | 38.52 ± 2.76 | 37.36 ± 3.46 | 3.51 | 0.17 |
Heart rate (bpm) | 468 ± 5 | 476 ± 8 | 464 ± 5 | 443 ± 4 | 2.57 | 0.26 |
LV end diastole | ||||||
LVAWT (mm) | 1.02 ± 0.04 | 1.62 ± 0.05 | 1.69 ± 0.04 | 1.23 ± 0.05** | 5.76 | 0.04 |
IVS (mm) | 0.71 ± 0.03 | 1.02 ± 0.03* | 1.05 ± 0.02 | 0.76 ± 0.02** | 6.89 | 0.03 |
LVEDD (mm) | 3.54 ± 0.05 | 2.58 ± 0.05* | 2.67 ± 0.03 | 2.91 ± 0.04** | 5.98 | 0.04 |
LV volume (μL) | 47.88 ± 0.40 | 35.46 ± 0.51* | 48.02 ± 0.54 | 38.66 ± 0.43** | 6.92 | 0.03 |
LV end systole | ||||||
LVAWT (mm) | 1.32 ± 0.06 | 1.76 ± 0.04* | 1.80 ± 0.02 | 1.42 ± 0.03** | 5.39 | 0.04 |
IVS (mm) | 0.99 ± 0.03 | 1.03 ± 0.01 | 1.01 ± 0.05 | 1.00 ± 0.02 | 2.15 | 0.28 |
LVESD (mm) | 2.29 ± 0.02 | 1.67 ± 0.03* | 1.58 ± 0.02 | 2.09 ± 0.02** | 5.75 | 0.04 |
LV volume (μL) | 22.54 ± 0.34 | 12.51 ± 0.28* | 11.18 ± 0.22 | 19.28 ± 0.32** | 5.66 | 0.04 |
AA, anacardic acid; IVS, interventricular septum; LVAWT, left ventricular anterior wall thickness; LVEDD, left ventricular end diastolic dimension; LVESD, left ventricular end systolic dimension; TAC, thoraic aorta coarctation.
P < 0.05 TAC vs normal group.
P < 0.05 TAC + AA vs TAC + Veh.