Table 3.
Supraspinal CNS regions anterogradely traced from lumbar spinal cord GRP neuronsa
| Brain area | Region | Stained cells |
|---|---|---|
| Cortical plate | Agranular insular cortex (AI) | + |
| Primary somatosensory cortex hindlimb region (S1HL) | ++ | |
| Cortical subplate | Central nucleus of the amygdala (CeA) | + |
| Pallidum | Extended amygdala (EA) | + |
| Hypothalamus | Medial preoptic nucleus (MPO) | + |
| Paraventricular hypothalamic nucleus posterior part (PaPo) | +++ | |
| Dorsomedial hypothalamic nucleus (DM) | ++ | |
| Lateral hypothalamic area (LHA) | + | |
| Thalamus | Paraventricular thalamic nucleus anterior part (PVA) | + |
| Paratenial thalamic nucleus (PT) | + | |
| Ventrolateral thalamic nucleus (VL) | ++ | |
| Paraventricular thalamic nucleus (PV) | + | |
| Mediodorsal thalamic nucleus medial part (MDM) | + | |
| Interanteromedial thalamic nucleus (IAM) | + | |
| Midline thalamic nuclei (MTN) | + | |
| Ventromedial thalamic nucleus (VM) | + | |
| Midbrain | Red nucleus (R) | +++ |
| Periaqueductal gray (PAG) | ++ | |
| Ventrolateral periaqueductal gray (VLPAG) | ++ | |
| Mesencephalic reticular formation (mRt) | ++ | |
| Median raphe nucleus (MRN) | + | |
| Isthmic reticular formation (isRT) | ++ | |
| Superior colliculus (SC) | + | |
| Dorsal raphe (DR) | +++ | |
| Pons | Pontine nuclei (Pn) | + |
| Locus coeruleus (LC) | +++ | |
| Medial parabrachial nucleus (MPB) | +++ | |
| Lateral parabrachial nucleus (LPB) | ++ | |
| Cerebellar nuclei | Deep cerebellar nuclei (DCN) | ++ |
| Lateral cerebellar nucleus (Lat) | + | |
| Medulla | Intermediate reticular nucleus (iRt) | ++ |
| Raphe magnus nucleus (RMg) | ++ | |
| Spinal vestibular nucleus (SpVe) | ++ | |
| Raphe obscurus nucleus (Rob) | +++ | |
| Lateral paragigantocellular nucleus (LPGi) | ++ |
aData are from 3 mice. +, low density; ++, high density; +++, very high density.