Table 1.

Study cohort characterization. Smoking is assessed based on past or current history of smoking (ever/never).

	AIS
n	882
Age (mean (sd); n missing)	65.23 (14.79; 4)
Sex = Male (%; n missing)	542 (61.7; 4)
Smoking (%; n missing)	559 (64.2; 11)
HTN (%; n missing)	558 (63.6; 5)
DM2 (%; n missing)	173 (19.7; 5)
HLD (%; n missing)	362 (41.3; 5)
SV (%; n missing)	85 (11.8; 162)
CE (%; n missing)	263 (36.5; 162)
LA (%; n missing)	164 (22.8; 162)
Other (%; n missing)	167 (23.2; 162)
TIA (%; n missing)	68 (7.8; 6)
Prior stroke (%; n missing)	138 (15.7; 4)
WMHv (mean (sd); n missing)	11.58 (13.49)
DWIv (mean (sd); n missing)	13.52 (28.61; 238)