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. 2019 Mar 19;10:258. doi: 10.3389/fphar.2019.00258

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Copyright © 2019 Zhu, Shi, Cao, Han, Liu, Qi, Huang, Zhu, Qian and Duan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Jia-Wei-Kai-Xin-San treatment increased acetylcholine levels, inhibited AChE activities and induced ChAT activities in hippocampus of Aβ injection mice. Animal group and drug treatment were same as that in Figure 2. After drug treatment, hippocampus tissues were isolated from the brains of animals. The amounts of acetylcholine (ACh) and activities of acetylcholinesterase (AChE) and acetyltransferase (ChAT) were analyzed by described method. Values are expressed in the percentage of control group as the Mean ± SEM (n = 8). ^#p < 0.05 (compared with sham group), ^∗p < 0.05, ^∗∗p < 0.01 (compared with model group).