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. 2019 Mar 19;13:105. doi: 10.3389/fncel.2019.00105

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Copyright © 2019 Shen, Feng, Zhang, Chen, Gao, Ke, Chen, Lin, Li, Iqbal, Zhao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Some of differentially expressed proteins were detected in PBMCs and pro-inflammatory cytokines were detected in plasma of children with autism by enzyme-linked immunosorbent assay (ELISA) analysis. (A) Calreticulin (CALR). Autism and control group, n = 28. (B) Alpha-1-antitrypsin (SERPINA1). Autism and control group, n = 29. (C) Interferon-γ (IFN-γ). Autism and control group, n = 30. (D) Interleukin-1β (IL-1β). Autism and control group, n = 28. (E) Interleukin-6 (IL-6). Autism and control group, n = 23. (F) IL-12. Autism and control group, n = 30. (G) Tumor necrosis factor-α (TNF-α). Autism and control group, n = 25. The graphical results depict the mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001. CALR and SERPINA1 were detected in PBMCs and others pro-inflammatory cytokines were detected in plasma.