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. 2019 Mar 19;10:247. doi: 10.3389/fneur.2019.00247

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Copyright © 2019 Shim, Kim, Kim and Baek.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subcortical structures segmented in Patients and Controls for comparison using FIRST. Top panel: Segmentation of white and gray matter generated by SIENAX overlaid on a subject's brain. Middle panel: Series of pictures of red outlines that represent segmented subcortical structures overlaid on top of the subject's T1-weighted brain. These pictures are examined for quality assessment purposes. Bottom panel: Subcortical structures segmented using FIRST, overlaid on top of the subject's skull stripped T1 weighted brain. Bilateral caudate, putamen, nucleus accumbens, thalamus, globus pallidus, amygdala, and hippocampus were segmented in both patients and controls.