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. 2019 Mar 19;10:275. doi: 10.3389/fphys.2019.00275

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Copyright © 2019 Gu, Yang, Guo, Zhang, Lin, Liu and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sample dendrogram and trait heatmap. The leaves of the tree correspond to osteoarthritis (OA) samples and non-steoarthritis (non-OA) samples. The first color band underneath the tree indicates which arrays appear to be outlying. The second color band represents disease stages which indicate OA and non-OA (red indicates high values). The third color band represents tissue sources which indicate samples from knee lateral tibial (LT) and medial tibial (MT) (red indicates high values). Similarly, the remaining color-bands color-code the numeric values of physiologic traits.