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. 2019 Mar 19;10:421. doi: 10.3389/fimmu.2019.00421

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Copyright © 2019 Tamgue, Gcanga, Ozturk, Whitehead, Pillay, Jacobs, Roy, Schmeier, Davids, Medvedeva, Dheda, Suzuki, Brombacher and Guler.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of miR-143/miR-365 target genes in macrophages. (A) Workflow for miR-143/miR-365 target genes prediction. (B) MiR-143/miR-365 predicted target genes expression in BMDMs. Data was previously generated in collaboration with the Fantom5 consortium (24) where BMDMs were classically (IFNγ) or alternatively (IL-4 and IL-13) activated then infected with the hypervirulent Mtb HN878 strain for different duration. RNA samples were collected and analyzed by CAGE transcriptomics. Gene expression is quantified as Tags Per Million (TPM).