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. 2019 Mar 19;10:488. doi: 10.3389/fimmu.2019.00488

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Copyright © 2019 Lu, McComish, Burdon, Taylor and Körner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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VDR, PU.1, FAIRE identify different SE regions with different genes nearby and gene function enrichment, respectively. (A) The (signal density)/(density rank) curve for SE calling from VDR, PU.1 and FARIE. (B) The number of enhancers (E) and super-enhancers (SE) before and after 1,25(OH)₂D₃ stimulation. (C) The Venn overlap figure for the gene list near VSE, PSE and FSE in 50 kb regions. VSE, VDR SE; PSE, PU.1 SE; FSE, FAIRE SE. (D) The enrichment analysis of GO biological process gene set for VSE, PSE and FSE; orange bar: the shared process between VSE and PSE (GEO data shown in Table 1).