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. 2019 Mar 19;10:488. doi: 10.3389/fimmu.2019.00488

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Copyright © 2019 Lu, McComish, Burdon, Taylor and Körner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The association of MS risk SNPs and ZMIZ1 gene set with VSE. (A) MS risk SNP enrichment in different SE regions. (B) VSE2-regulated genes are enriched in ZMIZ1 positively associated genes with higher log₂(fold change) (above); The names of these enriched VSE2-regulated genes (below). (C) VSE3-regulated genes are enriched in ZMIZ1 positively associated genes with higher average log₂(expression) (above); The names of these enriched VSE3-regulated genes (below). (D) Visualization of signal densities and VSE region around ZMIZ1 gene.