Table 1.

Reported expression of microRNAs identified in NAFLD, NASH and fibrosis patients.

Non-coding RNAs	Liver Disease	Tissue Expression	Circulating Expression
miR-122	NAFLD	Reduced (Latorre et al., 2017)	Increased (Cermelli et al., 2011; Yamada et al., 2013; Tan et al., 2014; Pirola et al., 2015; Liu et al., 2016; Salvoza et al., 2016; Brandt et al., 2018)
	NASH	Reduced (Cheung et al., 2008; Pirola et al., 2015; Aitana et al., 2016)	Increased (Becker et al., 2015; Pirola et al., 2015; Liu et al., 2016)
	Fibrosis	Reduced (Miyaaki et al., 2014)	Reduced (Miyaaki et al., 2014; Akuta et al., 2016)
miR-34a	NAFLD	NA	Increased (Cermelli et al., 2011; Yamada et al., 2013; Salvoza et al., 2016)
	NASH	Increased (Cheung et al., 2008; Aitana et al., 2016)	Increased (Liu et al., 2016)
miR-33a/b	NASH	Increased (Joel et al., 2016)	NA
miR-103/miR-107	NAFLD	NA	Increased (Xu Q. et al., 2015)
miR-21	NAFLD	NA	Increased (Yamada et al., 2013; Liu et al., 2016)
	NASH	NA	Increased (Becker et al., 2015)
miR-192	NAFLD	NA	Increased (Tan et al., 2014; Pirola et al., 2015; Liu et al., 2016)
	NASH	Reduced (Pirola et al., 2015)	Increased (Becker et al., 2015; Pirola et al., 2015; Liu et al., 2016)
miR-223	NAFLD	Reduced	Increased
	NASH	Reduced	Increased (Becker et al., 2015)
miR-29c	NASH	Reduced (Aitana et al., 2016)	NA
miR-181d, miR-99a, miR-197	NASH	NA	Reduced (Celikbilek et al., 2014)
miR-16	NASH	NA	Increased (Cermelli et al., 2011; Liu et al., 2016)
miR-146b	NAFLD	Reduced (Latorre et al., 2017)	Increased (Liu et al., 2016)
	NASH	Increased (Cheung et al., 2008)	Reduced (Celikbilek et al., 2014)
miR-19a, miR-19b, miR-125, miR-375	NAFLD	Reduced	Increased (Pirola et al., 2015)
	NASH	Reduced	Increased (Pirola et al., 2015)
miR-1290, miR-27b, miR-148a	NAFLD	NA	Increased (Tan et al., 2014)
miR-99a	NAFLD	NA	Increased (Tan et al., 2014)
	NASH	NA	Reduced (Celikbilek et al., 2014)
miR-139, miR-30b, miR-442	NAFLD	Reduced (Latorre et al., 2017)	NA
miR-451	NAFLD	NA	Increased (Yamada et al., 2013)