. 2019 Mar 25;15(4):51. doi: 10.1007/s11306-019-1511-8

Table 1.

List of metabolites with significant changes in the experimental treatments (p ≤ 0.01)

Compound	Ambient	Elevated [CO₂]		Elevated Temperature		Combination
Compound	Log₂(x̃) ± SE	Log₂(x̃) ± SE	Log₂(FC)	Log₂(x̃) ± SE	Log₂(FC)	Log₂(x̃) ± SE	Log₂(FC)
1,3-Diaminopropane	9.21 ± 0.27	9.81 ± 0.23	0.60	10.91 ± 0.13	*1.70*	9.95 ± 0.24	0.75
1-Benzylglucopyranoside	9.61 ± 0.21	10.56 ± 0.17	0.95	10.89 ± 0.26	*1.28*	10.76 ± 0.15	*1.15*
2-Methylmalic acid	11.27 ± 0.48	8.25 ± 0.17	− 3.02	9.60 ± 0.17	− 1.67	10.30 ± 0.38	− 0.97
α-ketoglutaric acid	9.93 ± 0.33	7.78 ± 0.21	− 2.15	10.57 ± 0.25	0.63	9.21 ± 0.25	− 0.72
α-tocopherol	10.85 ± 0.23	11.44 ± 0.23	0.59	12.25 ± 0.30	1.41	12.43 ± 0.16	1.58
γ-tocopherol	8.48 ± 0.17	8.90 ± 0.14	0.42	9.12 ± 0.18	0.64	8.26 ± 0.12	− 0.22
Arabinose	12.68 ± 0.12	13.21 ± 0.17	0.52	13.92 ± 0.25	*1.24*	13.34 ± 0.25	0.65
Arabitol	10.90 ± 0.22	11.61 ± 0.26*	0.71	11.67 ± 0.14	0.77	11.02 ± 0.16	0.12
Dehydroascorbic acid	11.54 ± 0.21	11.81 ± 0.14	0.27	12.57 ± 0.15	*1.02*	11.71 ± 0.19	0.17
Ethanolamine	14.58 ± 0.15	15.07 ± 0.13*	0.49	15.23 ± 0.11	0.65	14.70 ± 0.16	0.12
Fructose	20.19 ± 0.19	20.57 ± 0.21	0.38	21.27 ± 0.11	*1.08*	20.38 ± 0.23	0.19
Galactose	15.85 ± 0.18	16.71 ± 0.21	0.87	16.88 ± 0.18	*1.03*	16.22 ± 0.20	0.37
Gluconic acid	10.03 ± 0.05	10.68 ± 0.23	0.65	10.98 ± 0.17	0.95	10.77 ± 0.20	0.74
Glucose	20.55 ± 0.08	21.10 ± 0.21*	0.55	21.47 ± 0.09	0.92	20.54 ± 0.23	− 0.01
Glyceric acid	16.47 ± 0.12	17.20 ± 0.09	0.72	17.25 ± 0.15	0.78	16.54 ± 0.20	0.07
Inositol	14.78 ± 0.18	15.50 ± 0.19	0.71	15.83 ± 0.15	*1.05*	15.47 ± 0.16	0.68
Isoleucine	9.59 ± 0.17	10.40 ± 0.25	0.81	10.75 ± 0.22	*1.16*	10.58 ± 0.25	*0.98*
Leucine	9.45 ± 0.33	10.11 ± 0.11	0.66	10.95 ± 0.39	*1.50*	10.44 ± 0.35	*0.98*
Maltose	15.06 ± 0.15	15.50 ± 0.14	0.44	15.74 ± 0.07	0.68	14.98 ± 0.26	− 0.08
Melibiose	11.08 ± 0.23	11.91 ± 0.19	0.84	13.02 ± 0.27	*1.94*	12.24 ± 0.37	*1.17*
Neochlorogenic acid	16.72 ± 0.21	16.96 ± 0.11	0.24	17.32 ± 0.14	0.60	17.17 ± 0.13	0.45
O-acetylsalicylic acid	10.73 ± 0.11	11.00 ± 0.12	0.27	11.79 ± 0.19	*1.06*	11.09 ± 0.22	0.36
Oxalic acid	13.46 ± 0.16	13.54 ± 0.15	0.08	11.92 ± 0.31	− 1.54	12.04 ± 0.31	− 1.42
Phenylalanine	9.49 ± 0.13	9.83 ± 0.21	0.34	10.76 ± 0.36	*1.27*	10.81 ± 0.40	*1.31*
Quinic acid	17.30 ± 0.22	18.22 ± 0.12	0.92	18.14 ± 0.12	0.84	17.68 ± 0.13	0.39
Ribitiol	10.25 ± 0.25	10.81 ± 0.17	0.55	11.57 ± 0.21	*1.32*	10.90 ± 0.22*	0.64
Ribose	14.92 ± 0.17	15.25 ± 0.10	0.33	15.56 ± 0.12	0.64	15.13 ± 0.18	0.21
Serine	14.04 ± 0.11	13.92 ± 0.11	− 0.12	15.15 ± 0.16	*1.11*	14.36 ± 0.26	0.32
Sinapic acid	7.30 ± 0.19	7.74 ± 0.15	0.45	7.99 ± 0.20	0.69	7.98 ± 0.18	0.69
Stigmasterol	11.52 ± 0.14	12.14 ± 0.25	0.62	12.75 ± 0.22	*1.23*	12.65 ± 0.15*	*1.13*
Threitol	8.97 ± 0.12	9.28 ± 0.09	0.31	10.23 ± 0.15	*1.26*	9.78 ± 0.16	0.81
Threonine	11.90 ± 0.29	12.38 ± 0.11	0.46	13.30 ± 0.12	*1.38*	12.77 ± 0.26	0.85
Valine	10.57 ± 0.40	11.19 ± 0.15*	0.61	12.22 ± 0.18	*1.64*	11.91 ± 0.26	*1.34*
Xylose	8.80 ± 0.20	9.71 ± 0.15*	0.91	10.26 ± 0.26	*1.46*	10.08 ± 0.26	*1.27*

The log₂ normalized median values ± standard error and log₂fold change (log₂(FC)) for each treatment are shown. Metabolites significantly changed are denoted by bold value (p ≤ 0.01) or *(p ≤ 0.05). Bold italic cells show increased metabolite content and italics represents decreased metabolite content in the treatments