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. 2019 Mar 25;9:5078. doi: 10.1038/s41598-019-41532-3

Figure 4.

Figure 4

Table of potential pharmacokinetic interactions between herbal medicines and anticancer agents. Properties of herbal medicines in metabolic/transport pathways: Red = inhibition, green = induction, violet = controversial in references (inhibition and/or induction), blue: metabolic/transporter pathway, italic blue = metabolic pathway leading to a major active metabolite; 3A4 = cytochrome P450 3A4 (etc.); P-gp = P-glycoprotein; OCT = organic cation transport; DPD = dihydropyrimidine dehydrogenase. References used to build the table can be found online in Supplementary Data S3 and Supplementary Table S4.