FIG 1.

Differential gene regulation in B. cereus strain F837/76 after 3 h of growth in mMOD minimal medium with 0.25% PGM. Genes with detected P values of ≤0.05 and a fold change of >2 were considered. Hypothetical proteins were excluded. Differentially regulated genes were allocated to Clusters of Orthologous Groups (COG) categories (27, 28) using NCBI Conserved Domains Search (https://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi). Five hundred fifty-nine genes were upregulated in the presence of PGM, of which 68 belong to more than one COG category. These genes are shown as light gray bars. Six hundred twenty-two genes were downregulated in the presence of PGM, of which 73 are assigned to more than one COG category. They are shown as dark gray bars.