Table 1.
Echocardiography measurements of systolic function in 14‐month‐old mice
| mdx Con | mdx Sim | WT | mdx Con v mdx Sim P Value | mdx Con v WT P Value | mdx Sim v WT P Value | |
|---|---|---|---|---|---|---|
| n | 6 | 7 | 6 | |||
| Body weight | 34.2 ± 0.8 | 33.8 ± 0.6 | 36.5 ± 0.7 | NS | P < 0.05 | P < 0.05 |
| Heart rate | 627 ± 8 | 651 ± 5 | 638 ± 19 | NS | NS | NS |
| FS (%) | 45.2 ± 0.9 | 45.3 ± 1.0 | 47.0 ± 1.5 | NS | NS | NS |
| EF (%) | 78.1 ± 1.0 | 78.0 ± 0.9 | 79.4 ± 1.6 | NS | NS | NS |
Echocardiography parameters and statistical differences for mdx Con (n = 6), mdx Sim (n = 7) and WT (n = 6) as measured at the end of the experiment (after 8 weeks of Simvastatin treatment). Note that % fractional shortening (FS%) and ejection fraction (EF%) were not statistically different between any group. Values are mean (±SEM).