Skip to main content
. 2017 Jul 4;37(4):BSR20170327. doi: 10.1042/BSR20170327

Figure 4. PTEN is a direct target of miR-214.

Figure 4

(A) Wild-type or mutant miR-214 target sequences in the human PTEN 3′-untranslated region (3′-UTR). (B) Luciferase reporter assay of wild-type or mutant PTEN 3′-UTR reporter. (C) Western blotting analysis of PTEN and Akt expression in ovarian cancer cells. (D) Relative PTEN mRNA expression in ovarian cancer cells. (E) Relative PTEN mRNA expression in tumor specimen. Each experiment was performed in triplicate; **P<0.01 and *P<0.05. Data were presented as mean ± SD.