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. 2019 Feb 26;17(4):3181–3188. doi: 10.3892/etm.2019.7317

Figure 5.

Figure 5.

IRE1α and IRE1β protein expression is decreased in mice receiving AOM/DSS treatment. Following a one-off treatment with AOM and three cycles of DSS, tumor tissues from mice in the tumor group (n=10) and colon tissues from mice in the untreated control group (n=10) were collected. (A) IRE1α and (B) IRE1β protein expression was assessed by western blotting. The reduction of IRE1α expression was not significant, but the expression of IRE1β decreased significantly. *P<0.05 vs. control group. AOM, azoxymethane; DSS, dextran sulfate sodium; IRE, inositol-requiring enzyme.