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. 2019 Feb 26;17(4):3101–3107. doi: 10.3892/etm.2019.7315

Figure 2.

Figure 2.

Hyperoxia increases apoptosis in IL-6 null mice. (A) TUNEL staining results from 4-day old WT and IL-6 null mice exposed to normoxia (room air) or hyperoxia (85% oxygen). TUNEL-positive staining was indicated with green arrows. (B) TUNEL-positive cells were examined in 4-day old WT and IL-6 null mice exposed to normoxia or hyperoxia. (C) The relative protein expression levels of cleaved caspase-8, caspase-6 and caspase-3 was determined by western blot analysis. *P<0.05, **P<0.01 vs. normoxia. #P<0.05 vs. WT. IL-6−/−, IL-6 null mice; WT, wild-type; TUNEL, Terminal deoxynucleotidyl-transferase-mediated dUTP nick end labeling; IL, interleukin.