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Attenuation of oxidative stress and apoptosis by miR-25-targeting of MOAP1. VSMCs were transfected with pre-miR-25 and pcDNA-MOAP1 for 24 h. Expressions of MOAP1 were measured by qRT-PCR and western blot (a, b); ROS were measured using an OxiSelect ROS assay kit (c); apoptosis was detected by TUNEL assay (d). Results are expressed as mean ± S.E.M.∗∗p < 0.01. Crt: control vector; OE-miR-25: pre-miR-25.
