Table 3.
Genotypes distribution in cases and controls.
| Gene | SNP | Genotype | Cases | Controls | p | OR (95% CI) |
|---|---|---|---|---|---|---|
| (n=55) | (n=110) | |||||
| GPR54 | rs10407968 | A/G | ||||
| AA | 37 (67%) | 75 (65%) | 1a | |||
| AG | 18 (33%) | 31 (27%) | 0.649 | 0.850 (0.421 – 1.714) | ||
| GG | 00 | 09 (8%) | 0.038 | 0.893 (0.829 – 0.962) | ||
| AG + GG | 18 (33%) | 40 (35% | 0.791 | 1.096 (0.555 – 2.167) | ||
| GPR54 | rs1250729403 | T/G | ||||
| TT | 40 (71%) | 90 (78%) | 1a | |||
| TG | 15 (27%) | 25 (22%) | 0.389 | 0.722 (0.344 – 1.517) | ||
| GG | 00 | 00 | ||||
| GPR54 | rs350131 | G/T | ||||
| GG | 09 (16%) | 24 (21%) | 1a | |||
| GT | 26 (47%) | 53 (46%) | 0.557 | 0.764 (0.311 – 1.877) | ||
| TT | 20 (36%) | 38 (33%) | 0.478 | 0.713 (0.279 – 1.821) | ||
| GT + TT | 46 (84%) | 91 (79%) | 0.487 | 0.742 (0.319 – 1.726) | ||
| GPR54 | Chr19: 918686 | A/G | ||||
| Gene:6345 | ||||||
| AA | 37 (67%) | 84 (73%) | 1a | |||
| AG | 18 (33%) | 31 (27%) | 0.394 | 0.738 (0.367 – 1.486) | ||
| GG | 00 | 00 | ||||
| GPR54 | Chr19: 918735 | A/G | ||||
| Gene:6394 | ||||||
| AA | 26 (47%) | 56 (49%) | 1a | |||
| AG | 28 (51%) | 59 (51%) | 0.947 | 0.978 (0.512 – 1.868) | ||
| GG | 00 | 00 | ||||
| KISS1 | rs5780218 | CTT/CT | ||||
| CTT/CTT | 37 (67%) | 68 (59%) | 1a | |||
| CTT/CT | 14 (25%) | 42 (36%) | 0.184 | 1.632 (0.790 – 3.372) | ||
| CT/CT | 04 (7%) | 05 (4%) | 0.581 | 0.680 (0.172 – 2.688) | ||
| CTT/CT+ CT/CT | 18 (32%) | 47 (40%) | 0.307 | 1.421 (0.723 – 2.790) | ||
| KISS1 | rs4889 | C/G | ||||
| CC | 38 (69%) | 67 (58%) | 1a | |||
| CG | 16 (29%) | 42 (36%) | 0.264 | 1.489 (0.739 – 2.998) | ||
| GG | 01 (2%) | 06 (5%) | 0.239 | 3.403 (0.395 – 29.334) | ||
| CG + GG | 17 (31%) | 48 (41%) | 0.174 | 1.601 (0.810 – 3.166) |
OR: odds ratio; CI: confidence intervals; a reference genotype.