Table 4.
Blood cell count in rats infected with Shigella flexneri after treatment with C. jagus water/ethanol extract and ciprofloxacin.
| Groups | NC | TD | Cipro | WECj25 | WECj50 | WECj100 |
|---|---|---|---|---|---|---|
| WBCX103/mm3 | 5.24 ± 0.14 | 2.74 ± 0.75∗∗ | 3.92 ± 0.22 | 4.79 ± 0.08b | 4.92 ± 0.55b | 5.22 ± 0.32a |
| RBCX106/mm3 | 4.28 ± 0.19 | 6.42 ± 0.45 | 7.06 ± 0.35∗ | 7.82 ± 1.19∗∗ | 7.37 ± 0.51∗∗ | 8.25 ± 0.39∗∗ |
| Hb (g/dL) | 13.15 ± 0.76 | 11.16 ± 0.80 | 12.18 ± 0.93 | 12.32 ± 0.74 | 13.14 ± 0.54 | 12.30 ± 0.62 |
| Ht (%) | 40.04 ± 1.76 | 34.32 ± 1.93 | 36.68 ± 2.25 | 40.52 ± 1.67 | 42.64 ± 3.30b | 44.40 ± 0.86b |
| PcX106/mm3 | 373.40 ± 1.13 | 374.80 ± 2.05 | 361.80 ± 4.72b | 485.64 ± 3.02∗∗a | 497.20 ± 2.15∗∗a | 826.60 ± 2.89∗∗a |
| MGV (μm3) | 59.98 ± 2.06 | 52.20 ± 0.53∗ | 51.80 ± 0.73∗∗ | 54.00 ± 0.84∗ | 52.20 ± 0.86∗ | 53.20 ± 0.97∗ |
| MGH (ρg) | 34.02 ± 3.79 | 17.40 ± 0.08∗∗ | 17.40 ± 0.22∗∗ | 14.26 ± 2.81∗∗ | 16.60 ± 0.97∗∗ | 14.56 ± 1.39∗∗ |
| MCHC (ρg/dL) | 31.56 ± 2.07 | 33.46 ± 0.38 | 33.46 ± 0.47 | 33.78 ± 0.84 | 34.74 ± 0.66 | 35.04 ± 0.97 |
WECj25, WECj50, and WECj100: C. jagus water/ethanol extract of 25, 50, and 100 mg/kg; Cipro: ciprofloxacin 2.5 mg/kg; NC: normal control; DC: diarrheic control; WBC: white blood cell; Hb: haemoglobin; Ht: hematocrit; RBC: red blood cell; Pc: platelets; MGV: mean globular volume; MGH: mean globular haemoglobin; MCHC: mean corpuscular haemoglobin concentration (n=5). Significant difference: ∗p<0.05 and ∗∗p<0.01 compared to normal control (NC); ap<0.01 and bp<0.05 compared to diarrheic control (DC).