Fig. 4.

Real-time RT-PCR analysis after application of Noggin in chick maxillary mesenchyme. The chart shows real-time RT-PCR results for different genes from maxillary mesenchyme treated with BSA and Noggin. Each bar shows BSA treated sample on the left and experimental situation on the right. Bmp4 and Wnt3a gene expression significantly increased after Noggin-soaked bead implantation in the maxillary prominences, whereas Sox9 gene expression decreased. Values are the mean ± S.E. in separate experiments using 9 embryos. *: P < 0.05, significantly different from the corresponding value for BSA treated group.