Table 2. Echocardiographic findings.
Parameters | Sham | Infarction treated with | ||||
Vehicle | Vehicle | OM | OM + Vit C | OM + ARB | FM | |
No. of rats | 10 | 10 | 11 | 11 | 12 | 10 |
IVS (mm) | 1.4 ± 0.1 | 0.5 ± 0.2* | 0.6 ± 0.2* | 0.6 ± 0.2* | 0.6 ± 0.1* | 0.6 ± 0.1* |
LVEDD (mm) | 5.7 ± 0.2 | 8.6 ± 0.2* | 9.1 ± 0.2*# | 7.7 ± 0.2*#† | 7.5 ± 0.1*#† | 8.5 ± 0.2*† |
LVESD (mm) | 3.5 ± 0.2 | 6.9 ± 0.2* | 7.7 ± 0.2*# | 5.8 ± 0.2*#† | 5.5 ± 0.3*#† | 6.9 ± 0.1*† |
LV posterior wall (mm) | 1.4 ± 0.1 | 1.7 ± 0.2* | 2.0 ± 0.1*# | 1.7 ± 0.1*† | 1.7 ± 0.2*† | 1.8 ± 0.2* |
FS (%) | 39 ± 2 | 20 ± 3* | 15 ± 3*# | 24 ± 3*† | 26 ± 3*#† | 19 ± 2*† |
Values are mean ± SD.
Abbreviations as in Table 1. FS, fractional shortening; IVS, interventricular septum; LVEDD, left ventricular end-diastolic dimension; LVESD, left ventricular end-systolic dimension.
* p < 0.05 compared with the sham group; # p < 0.05 compared with infarcted group treated with vehicle; † p < 0.05 compared with infarcted group treated with OM.