. 2019 Mar;35(2):144–152. doi: 10.6515/ACS.201903_35(2).20181231A

Supplementary data. Sensitivity analysis of heterogeneity on 24-h SBP.

Studies included	Studies (N)	IV 95% CI	p	I²
All studies	12	-2.08 (-4.93,0.77)	0.15	63
Studies with change rate < 35%*	8	-2.29 (-6.73, 2.15)	0.31	74
Studies with change rate < 30%^#	6	-3.24 (-7.7, 1.22)	0.15	73
Studies with change rate < 25%^†	5	-5.49 (-7.79, -3.2)	< 0.00001	0
Studies with change rate < 10%^‡	4	-6.07 (-8.68, -3.46)	< 0.00001	0

* Included studies: SYMPLICITY HTN-2 [1], OSLO [19], DENERVHTA, SYMPLICITY FLEX [18], DENERHTN [12], SYMPLICITY HTN-JAPAN [11], SPYRAL HTN-OFF MED [4], SPYRAL HTN-ON MED [5]. ^# Included studies: DENERVHTA, SYMPLICITY FLEX [18], DENERHTN [12], SYMPLICITY HTN-JAPAN [11], SPYRAL HTN-OFF MED [4], SPYRAL HTN-ON MED [5]. ^† Included studies: SYMPLICITY FLEX [18], DENERHTN [12], SYMPLICITY HTN-JAPAN [11], SPYRAL HTN-OFF MED [4], SPYRAL HTN-ON MED [5]. ^‡ Included studies: DENERHTN [12], SYMPLICITY HTN-JAPAN [11], SPYRAL HTN-OFF MED [4], SPYRAL HTN-ON MED [5].

N, number; IV 95% CI were calculated by RevMan 5.3.