Table 2. Individual data of the 4 patients who did not undergo pulmonary endarterectomy.

Variables	Case 1	Case 2	Case 3	Case 4*
Sex	Female	Female	Female	Female
Age, years	66	71	40	36
Follow-up period, months	69	64	119	44
Functional class
At diagnosis	III	III	III	IV
Last evaluation	IV	II	II	III
6MWD, m
At diagnosis	338	416	387	221
Last evaluation	286	390	429	390
Level of pulmonary artery stenosis by selective angiography#	Distal	Distal	Distal	Proximal (by CTA)
Cardiac catheterization
RAP, mmHg	15	8	10	8
SPAP, mmHg	123	68	65	96
MPAP, mmHg	74	43	46	61
PAWP, mmHg		12	14
CO, L/min	2.5	3.8	4
CI, L/min·m2	1.9	2.7	2.7
PVR, WU	29.2	5.3	8.2	8.0
MvO2, %	51	72	73
SaO2, %	88	92	95	77 (SpO2)
Reasons of no PEA	Patient’s refusal	Surgical inaccessible	Surgical inaccessible	Co-morbidities of SLE and APS
PAH-specific drugs	Sildenafil	Riociguat	Riociguat	Bosentan + sildenafil
Survival outcome	Expired	Alive	Alive	Expired

* Hemodynamic data by echocardiography; ^# Proximal lesions indicate main or lobal pulmonary artery stenosis, whilst distal lesions indicate segmental or subsegmental stenosis.

APS, antiphospholipid syndrome; CI, cardiac index; CO, cardiac output; CTA, CT angiography of chest; MPAP, mean pulmonary artery pressure; MvO₂, mixed venous oxygen saturation; PAH, pulmonary arterial hypertension; PAWP, pulmonary artery wedge pressure; PEA, pulmonary endarterectomy; PVR, pulmonary vascular resistance; RAP, right atrial pressure; SaO₂, arterial oxygen saturation; SLE, systemic lupus erythematosus; SPAP, systolic pulmonary artery pressure; SpO₂, oxyhemoglobin saturation by pulse oximetry; 6MWD, 6-minute walk distance.