Table 1.
EGFRvIII | P | ||
---|---|---|---|
Positive | Negative | ||
Total | 13 | 54 | |
Age | 66.5 | 63.8 | 0.223 |
Female sex | 4 (30.8%) | 28 (51.9%) | 0.540 |
Laterality | |||
Right | 8 (61.5%) | 27 (50.0%) | 0.736 |
Left | 4 (30.8%) | 20 (37.0%) | 0.302 |
Bilateral | 1 (7.7%) | 7 (13.0%) | 0.237 |
Tumor location | |||
Frontal | 5 (38.5%) | 26 (48.1%) | 0.758 |
Temporal | 3 (23.1%) | 14 (25.9%) | 0.999 |
Parietal | 1 (7.7%) | 3 (5.6%) | 0.999 |
Occipital | 2 (15.4%) | 1 (1.9%) | 0.094 |
Insular | 1 (7.6%) | 2 (3.7%) | 0.482 |
Corpus callosum | 1 (7.6%) | 2 (3.7%) | 0.482 |
Multiple | 0 | 6 (11.1%) | 0.588 |
Surgery | |||
GTR | 3 (23.1%) | 13 (24.0%) | 0.999 |
STR | 8 (61.5%) | 16 (29.6%) | 0.051 |
PR | 2 (15.4%) | 25 (46.3%) | 0.059 |
Radiation therapy | 13 (100%) | 52 (96.3%) | 0.999 |
Temozolomide | 12 (92.3%) | 51 (94.4%) | 0.999 |
Bevacizumab | 5 (%) | 7 (13.0%) | 0.204 |
Additional surgery | 2 (%) | 5 (9.3%) | 0.614 |
MGMT positivity | 7 (53.8) | 24 (44.4%) | 0.556 |
GTR: gross total resection, PR: partial resection, STR: subtotal resection.