Analysis of angiogenesis in the peri-infarct cortex at D21. (a)
Immunohistochemical staining at the peri-infarct cortex showed that
the RECA-1-positive area in the young human mesenchymal stem cell
(hMSC) group was significantly larger than in controls or the old
hMSC group. (b) The number of platelet-derived growth factor
receptor (PDGFR)-β-positive vessels in the young hMSC group was
higher than in controls or the old hMSC group (one-way ANOVA,
Tukey–Kramer multiple comparison test,
**P < 0.01). (c), (d) RECA-1 and PDGFR-β double
staining images at the peri-infarct cortex. Data are presented as
mean ± SD. Scale bar = 50 µm (c), 10 µm (d), magnified image.