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. 2018 Oct 18;243(13):1066–1073. doi: 10.1177/1535370218806455

Figure 5.

Figure 5.

Knockdown of WWOX induces chemotherapy chemoresistance. (a) The cell survival rates of control or WWOX-knockdown cells after treatment with CDDP (5 and 10 µg/ml), ADM (2.5 and 5 µM) and PTX (2.5 and 5 nM) for 24, 48 or 72 h. (b) Control or WWOX-silenced cells were treated with CDDP (5 µg/ml), ADM (5 µM), and PTX (5 nM) for 48 h, incubated with 7-AAD and PE, and then examined by FACS. (c) Clone formation in control or WWOX-silenced cells after treatment with CDDP (2.5 μg/ml), ADM (1 µM), and PTX (1 nM) for 14 days. (d) The percentage of apoptosis cells of control or WWOX-silenced cells upon CDDP, PTX, and ADM treatment.