Table 2.
Before matching | After matching | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
CRT | C + CRT | P | CRT | C + CRT | P | |||||
N | % | N | % | N | % | N | % | |||
Facility | ||||||||||
Nonacademic | 848 | 65 | 789 | 59 | 0.0085 | 548 | 62 | 539 | 61 | 0.70 |
Academic | 452 | 35 | 521 | 39 | 339 | 38 | 348 | 39 | ||
NA | 7 | 1 | 19 | 1 | 0 | 0 | 0 | 0 | ||
Age | ||||||||||
<66 | 674 | 52 | 762 | 57 | 0.0030 | 472 | 53 | 498 | 56 | 0.23 |
≥66 | 633 | 48 | 567 | 43 | 415 | 47 | 389 | 44 | ||
NA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
Gender | ||||||||||
Female | 645 | 49 | 663 | 50 | 0.79 | |||||
Male | 662 | 51 | 666 | 50 | ||||||
NA | 0 | 0 | 0 | 0 | ||||||
Race | ||||||||||
White | 1141 | 87 | 1148 | 86 | 0.19 | |||||
Black | 119 | 9 | 121 | 9 | ||||||
Other | 32 | 2 | 49 | 4 | ||||||
NA | 15 | 1 | 11 | 1 | ||||||
Insurance | ||||||||||
None | 31 | 2 | 34 | 3 | 0.071 | |||||
Nonprivate | 728 | 56 | 684 | 51 | ||||||
Private | 533 | 41 | 601 | 45 | ||||||
NA | 15 | 1 | 10 | 1 | ||||||
Income | ||||||||||
Above median | 733 | 56 | 870 | 65 | <0.001 | 547 | 62 | 563 | 63 | 0.46 |
Below median | 544 | 42 | 441 | 33 | 340 | 38 | 324 | 37 | ||
NA | 30 | 2 | 18 | 1 | 0 | 0 | 0 | 0 | ||
Residential setting | ||||||||||
Metro | 1023 | 78 | 1086 | 82 | 0.049 | |||||
Urban | 201 | 15 | 181 | 14 | ||||||
Rural | 31 | 2 | 18 | 1 | ||||||
NA | 52 | 4 | 44 | 3 | ||||||
Charlson‐Deyo Score | ||||||||||
0‐1 | 1235 | 94 | 1248 | 94 | 0.56 | 836 | 94 | 841 | 95 | 0.68 |
≥2 | 72 | 6 | 81 | 6 | 51 | 6 | 46 | 5 | ||
NA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
Year of diagnosis | ||||||||||
2004‐2007 | 210 | 16 | 74 | 6 | <0.001 | 69 | 8 | 47 | 5 | 0.11 |
2008‐2011 | 680 | 52 | 696 | 52 | 458 | 52 | 467 | 53 | ||
2012‐2015 | 417 | 32 | 559 | 42 | 360 | 41 | 373 | 42 | ||
NA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
Primary tumor site | ||||||||||
Head | 1076 | 82 | 1105 | 83 | 0.015 | |||||
Body | 78 | 6 | 105 | 8 | ||||||
Tail | 153 | 12 | 119 | 9 | ||||||
NA | 0 | 0 | 0 | 0 | ||||||
Tumor grade | ||||||||||
Well diff | 108 | 8 | 112 | 8 | 0.64 | 75 | 8 | 79 | 9 | 0.13 |
Mod diff | 629 | 48 | 652 | 49 | 460 | 52 | 478 | 54 | ||
Poor diff | 455 | 35 | 448 | 34 | 346 | 39 | 315 | 36 | ||
Other | 13 | 1 | 20 | 2 | 6 | 1 | 15 | 2 | ||
NA | 102 | 8 | 97 | 7 | 0 | 0 | 0 | 0 | ||
Tumor size (cm) | ||||||||||
<3.1 | 575 | 44 | 657 | 49 | 0.0050 | 410 | 46 | 410 | 46 | 1 |
≥3.1 | 697 | 53 | 636 | 48 | 477 | 54 | 477 | 54 | ||
NA | 35 | 3 | 36 | 3 | 0 | 0 | 0 | 0 | ||
Clinical T stage | ||||||||||
1 | 158 | 12 | 195 | 15 | 0.15 | |||||
2 | 517 | 40 | 509 | 38 | ||||||
3 | 632 | 48 | 625 | 47 | ||||||
NA | 0 | 0 | 0 | 0 | ||||||
Clinical N stage | ||||||||||
0 | 874 | 67 | 871 | 66 | 0.48 | |||||
1 | 433 | 33 | 458 | 34 | ||||||
NA | 0 | 0 | 0 | 0 | ||||||
Pathologic T stage | ||||||||||
0 | 1 | 0 | 1 | 0 | 0.61 | 1 | 0 | 1 | 0 | 0.95 |
1 | 49 | 4 | 45 | 3 | 30 | 3 | 36 | 4 | ||
2 | 169 | 13 | 153 | 12 | 108 | 12 | 105 | 12 | ||
3 | 980 | 75 | 1056 | 79 | 731 | 82 | 729 | 82 | ||
4 | 22 | 2 | 22 | 2 | 17 | 2 | 16 | 2 | ||
Other | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
NA | 86 | 7 | 52 | 4 | 0 | 0 | 0 | 0 | ||
Pathologic N stage | ||||||||||
0 | 338 | 26 | 293 | 22 | 0.0075 | 228 | 26 | 226 | 25 | 0.96 |
1 | 874 | 67 | 971 | 73 | 659 | 74 | 661 | 75 | ||
NA | 95 | 7 | 65 | 5 | 0 | 0 | 0 | 0 | ||
Number of positive lymph nodes | ||||||||||
0 | 363 | 28 | 297 | 22 | <0.001 | |||||
1‐3 | 585 | 45 | 585 | 44 | ||||||
4+ | 324 | 25 | 415 | 31 | ||||||
NA | 35 | 3 | 32 | 2 | ||||||
Surgery | ||||||||||
Whipple variant | 342 | 26 | 397 | 30 | 0.10 | 253 | 29 | 256 | 29 | 0.98 |
Whipple | 668 | 51 | 650 | 49 | 437 | 49 | 436 | 49 | ||
Other | 297 | 23 | 282 | 21 | 197 | 22 | 195 | 22 | ||
NA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
Surgical margin | ||||||||||
Negative | 891 | 68 | 968 | 73 | 0.012 | 643 | 72 | 637 | 72 | 0.79 |
Positive | 386 | 30 | 336 | 25 | 244 | 28 | 250 | 28 | ||
NA | 30 | 2 | 25 | 2 | 0 | 0 | 0 | 0 | ||
Chemotherapy | ||||||||||
Single agent | 824 | 63 | 766 | 58 | 0.0047 | 536 | 60 | 515 | 58 | 0.33 |
Multi agent | 483 | 37 | 563 | 42 | 351 | 40 | 372 | 42 | ||
NA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
Radiation dose (Gy) | ||||||||||
Median | 50.4 | 50.4 | 0.18 | 50.4 | 50.4 | 0.17 | ||||
IQR | 50.0‐54.0 | 50.0‐50.4 | 50.0‐54.0 | 50.0‐50.4 |
C, chemotherapy; CRT, chemoradiation; diff, differentiated; IQR, interquartile range; mod, moderately; NA, not available; poor, poorly.