Table 4.
Univariate and multivariate analysis of prognostic markers for overall survival in gastric cancer
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| HR | P > |z| | 95% CI | HR | P > |z| | 95% CI | |
| Vimentin expression | ||||||
| High vs Low or no | 2.167 | 0.017 * | 1.151‐4.079 | — | — | — |
| Trop2+/vimentin+ vs Trop2−/vimentin− | 1.603 | <0.001 * | 1.272‐2.019 | 1.544 | 0.007 * | 1.125‐2.119 |
| Age | ||||||
| <60 vs ≥60 | 0.629 | 0.074 | 0.378‐1.947 | — | — | — |
| Gender | ||||||
| Male vs Female | 1.238 | 0.463 | 0.700‐2.191 | — | — | — |
| Histological type | ||||||
| Tubular vs Mucinous vs signet ring cells vs othersa | 0.776 | 0.233 | 0.511‐1.178 | — | — | — |
| Differentiation | ||||||
| Well vs Moderate vs Poor | 2.244 | <0.001 * | 1.481‐3.400 | — | — | — |
| TNM stage | ||||||
| 0 vs Ia + Ib vs IIa + IIb vs IIIa + IIIb vs IIIc + IV | 6.949 | <0.001 * | 3.931‐12.285 | 5.731 | <0.001 * | 3.143‐10.452 |
| Tumor size | ||||||
| T0 vs T1a + T1b + T2 vs T3 + T4a + T4b | 2.387 | <0.001 * | 1.721‐3.310 | — | — | — |
| Distant metastases | ||||||
| M0 vs M1 | 2.297 | 0.002 * | 1.351‐3.905 | — | — | — |
a
Others include pallipary adenocarcinoma, 3 cases; adeno‐squamous carcinoma, 2 cases; and neuroendocrine carcinoma, 1 case.
*
P < 0.05.
Bold values are statistically significant.