FIG. 4.

T cell activation and intestinal barrier function post SIV infection. Activated peripheral blood CD4⁺ T cells expressing CCR5, CXCR3, or Ki-67 at week 4 pi (A). The nonparametric Mann–Whitney test was applied to determine statistically significant differences between groups. Both CD4⁺ and CD8⁺ T cells positive for the intestinal homing marker α4β7 correlated with peak viremia (B). Correlation analysis was performed using the Spearman rank test.