Antibody responses after SIV infection. Geometric mean concentrations of plasma IgG antibodies to (A) gp120, (B) gp41, and (C) gp70-V1V2 measured early after infection. (D–F) Comparison of peak viral loads and week 2 pi concentrations of anti-Env plasma antibodies. (G) inverse association between peak viral loads and the percentage increase in anti-gp120 IgG plasma antibody avidity from week 0 to 2 pi. IgA antibodies to (H) gp120 and (I) gp41 in fecal extracts of vaccinated and control infants. Fecal IgG antibodies to (J) gp120, (K) gp41, and (L) gp70-V1V2. (M–O) Inverse associations between peak viremia and anti-Env fecal IgG antibodies. All comparisons were done using the Spearman rank correlation test, and were only significant where p and r values are indicated.