Table 1.

Vaccination Groups and Schedule

Group	Prime (weeks 0 and 3)	Dose and route	Boost (weeks 6 and 9)	Dose and route	First oral SIVmac251 exposure
A (n = 6)	Saline	1 mL O + 0.25 mL IM	Empty MVA	108 PFU SL + 108 PFU IM	Week 12
B (n = 6)	DNA-SIVa	3.0 mg IMb	MVA-SIV	108 PFU IM	Week 12
C (n = 6)	DNA-SIV	1.5 mg O + 1.5 mg IMc	MVA-SIV	108 PFU SL + 108 PFU IM	Week 12

^aDNA-SIV: 1:1 mixture of D_G + D_40L.

^b1.5 mg D_G + 1.5 mg D_40L.

^c0.75 mg D_G + 0.75 mg D_40L by each route.

SIV, simian immunodeficiency virus; O, oral; IM, intramuscular; SL, sublingual; MVA, modified vaccinia Ankara; PFU, plaque forming units.