Figure 1. Brain metastases in RET-rearranged lung cancers.

In Figure 1A, the frequency of brain metastases at the time of diagnosis of stage IV disease is shown on the left. The lifetime prevalence of brain metastases in stage IV disease, including brain metastases at diagnosis, is shown on the right. In Figure 1B, the cumulative incidence of brain metastases in RET-rearranged lung cancers is compared to ALK- and ROS1-rearranged lung cancers for patients without known brain metastases at diagnosis.