Table 3.
Multivariate linear regression analyses for the relationship between serum potassium, transtubular potassium gradient, and urine angiotensinogen-creatinine ratio
| Variables | Dependent variables | |||
|---|---|---|---|---|
| Serum potassium | TTKG | |||
| β | p-value | β | p-value | |
| DM (vs. non-DM) | 0.171 | < 0.001 | – | – |
| BMI (kg/m2) | −0.047 | 0.044 | – | – |
| eGFR (mL/min/1. 73m2) | −0.315 | < 0.001 | 0.157 | < 0.001 |
| Total CO2 (mmol/L) | −0.152 | < 0.001 | 0.174 | < 0.001 |
| Serum albumin (g/dL) | 0.066 | 0.019 | – | – |
| UPCR (g/g)* | 0.120 | < 0.001 | – | – |
| Urine AGT/Cr ratio (μg/g)* | − 0.058 | 0.017 | 0.087 | 0.001 |
| Urine osmolality (mOsm/kg)* | − 0.056 | 0.046 | 0.118 | < 0.001 |
| Diuretics (vs. non-user) | – | – | ||
| Age (years) | – | – | 0.104 | < 0.001 |
| Sex (vs. female) | – | – | 0.139 | < 0.001 |
| Charlson comorbidity index | – | – | −1.000 | 0.002 |
β: Standardized coefficient
*Variables are log transformed
Abbreviations: TTKG, trans-tubular potassium gradient; DM, diabetes mellitus; BMI, body mass index; eGFR, estimated glomerular filtration; CO2, carbon dioxide; UPCR, urine protein-to-creatinine ratio; AGT/Cr, angiotensinogen/creatinine