Table 5.
Multivariable Cox regression analysis for composite outcome in patients with PKD
| Variables | Hazard ratio | 95% confidence interval | p-value |
|---|---|---|---|
| Age (year) | 1.00 | 0.96–1.04 | 0.964 |
| Sex (vs. female) | 0.72 | 0.34–1.51 | 0.383 |
| Baseline eGFR (mL/min/1. 73m2) | 0.91 | 0.88–0.93 | < 0.001 |
| SBP (vs. < 130 mmHg) | 2.02 | 1.03–3.97 | 0.042 |
| BMI (kg/m2) | 0.96 | 0.86–1.06 | 0.387 |
| Use of RAAS blocker (vs. non-user) | 1.29 | 0.42–3.95 | 0.655 |
| Macroalbuminuria (vs. normo- or microalbuminuria) | 1.40 | 0.56–3.48 | 0.468 |
| Urine AGT/Cr ratio (μg/g)a | 1.29 | 1.07–1.55 | 0.007 |
aVariable was log transformed
Abbreviations: eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; BMI, body mass index; RAAS, renin-angiotensin-aldosterone; AGT/Cr, angiotensinogen/creatinine