Table 2.
The diffusion metrics of corpus callosum subregions
| Region | FA | AD | RD | MD | ||||
|---|---|---|---|---|---|---|---|---|
| PT | HC | PT | HC | PT | HC | PT | HC | |
| Subregion 1 | 0.47 ± 0.05 | 0.48 ± 0.03 | 1.41 ± 0.09 | 1.36 ± 0.09 | 0.64 ± 0.10 | 0.60 ± 0.06 | 0.91 ± 0.09 | 0.85 ± 0.06 * |
| Subregion 2 | 0.54 ± 0.04 | 0.55 ± 0.02 | 1.40 ± 0.04 | 1.37 ± 0.04 * | 0.55 ± 0.06 | 0.52 ± 0.04 | 0.83 ± 0.05 | 0.80 ± 0.04 * |
| Subregion 3 | 0.49 ± 0.04 | 0.50 ± 0.03 | 1.39 ± 0.04 | 1.35 ± 0.05 * | 0.60 ± 0.06 | 0.58 ± 0.05 | 0.87 ± 0.05 | 0.83 ± 0.05 |
| Subregion 4 | 0.50 ± 0.04 | 0.50 ± 0.03 | 1.44 ± 0.04 | 1.41 ± 0.04 * | 0.62 ± 0.06 | 0.59 ± 0.05 | 0.89 ± 0.05 | 0.87 ± 0.04 |
| Subregion 5 | 0.49 ± 0.03 | 0.51 ± 0.03 | 1.47 ± 0.04 | 1.43 ± 0.05 * | 0.64 ± 0.06 | 0.60 ± 0.06 * | 0.92 ± 0.05 | 0.88 ± 0.05 * |
| Subregion 6 | 0.46 ± 0.03 | 0.49 ± 0.03 * | 1.53 ± 0.08 | 1.47 ± 0.05 ** | 0.71 ± 0.08 | 0.64 ± 0.06 ** | 0.98 ± 0.08 | 0.92 ± 0.05 ** |
| Subregion 7 | 0.55 ± 0.02 | 0.56 ± 0.02 | 1.57 ± 0.04 | 1.55 ± 0.05 | 0.59 ± 0.04 | 0.57 ± 0.04 | 0.92 ± 0.03 | 0.90 ± 0.04 |
| Whole CC | 0.53 ± 0.02 | 0.54 ± 0.02 | 1.50 ± 0.03 | 1.47 ± 0.04 * | 0.60 ± 0.04 | 0.57 ± 0.03 * | 0.90 ± 0.04 | 0.87 ± 0.03 * |
** P < 0.01, * 0.01 < P < 0.05
For illustration, all values of AD, RD and MD were multiplied by 1000
Abbreviations: CC corpus callosum, FA Fractional Anisotropy, AD axial diffusivity; RD radial diffusivity, MD Mean diffusivity, HC healthy controls, PT alcohol-dependent patients
Entries in boldface are diffusion metrics with significant inter-group differences (P < 0.05)